June 24, 2020: MBCF is Open!

New Sample Drop-off Policy

DFCI investigators:
Drop-off samples in the “Fish Room” or directly to our 21-27 Burlington Ave site by appointment.
Samples will be picked up from the Fish Room on Mondays, Tuesdays and Thursdays at 9am.
Please follow the new sample drop-off safety protocol posted in the Fish Room and HERE.

External investigators:
Drop-off samples at our Burlington Avenue location on Wednesdays and Fridays between noon-1pm by appointment  only or via FedEx.
Schedule a drop-off

In accordance with DFCI stage II re-opening policies, we are operating with limited staff and reduced shift hours. This may impact turnaround times…but hopefully not too much!

We are excited to be back in the lab!

Please email us with any questions.


The Molecular Biology Core Facilities (MBCF) at Dana-Farber Cancer institute (DFCI) provide expertise and access to cutting-edge genomic and proteomic technologies in a shared use setting. Although these services are primarily focused on cancer and AIDS research, most services are broadly applicable to other areas of research. We are proud to highlight some of our new services here.

Illumina NovaSeq 6000

  • High-throughput: 800M to 10B clusters/flowcell
  • Fast turnaround time for projects both small and large
  • Applications: Single-cell RNAseq, Whole Genome Sequencing, Methylation profiling…

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Amplicon Sequencing

  • Deep Sequencing of small amplicons (200-275bp)
  • >50,000x coverage
  • Great for CRISPR edit site characterization

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  • Library prep + Sequencing from immunoprecipitated DNA
  • Fixed cost per sample
  • QC analysis and Peak Calling (optional)
  • Fast turnaround time

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Copy Number Analysis

  • Ultra Low Pass Whole Genome Sequencing (ULP-WGS)
  • 100kb resolution

read more >