Welcome

COVID-19 UPDATE:

In accordance with DFCI COVID-19 prevention policies,

MBCF will not be accepting new projects or samples until further notice.

Please check back or email us for updates.

We apologize for the inconvenience and hope to see you (and your samples) again soon.

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The Molecular Biology Core Facilities (MBCF) at Dana-Farber Cancer institute (DFCI) provide expertise and access to cutting-edge genomic and proteomic technologies in a shared use setting. Although these services are primarily focused on cancer and AIDS research, most services are broadly applicable to other areas of research. We are proud to highlight some of our new services here.

Illumina NovaSeq 6000

  • High-throughput: 800M to 10B clusters/flowcell
  • Fast turnaround time for projects both small and large
  • Applications: Single-cell RNAseq, Whole Genome Sequencing, Methylation profiling‚Ķ

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Amplicon Sequencing

  • Deep Sequencing of small amplicons (200-275bp)
  • >50,000x coverage
  • Great for CRISPR edit site characterization

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ChIPseq

  • Library prep + Sequencing from immunoprecipitated DNA
  • Fixed cost per sample
  • QC analysis and Peak Calling (optional)
  • Fast turnaround time

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Copy Number Analysis

  • Ultra Low Pass Whole Genome Sequencing (ULP-WGS)
  • 100kb resolution

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