Copy Number Analysis (CNA)

by Ultra Low Pass Whole Genome Sequencing (ULP-WGS)

The approach uses low coverage whole genome sequencing to estimate copy number variation. Genomic DNA is fragmented and subsequently converted into an Illumina sequencing library. Approximately 5M library fragments are sequenced and analyzed for copy variation at 100kb resolution.

Pricing

QC + library prep + sequencing + analysis
DFCI/BWH: $200
External: $250

Turnaround

2 weeks

Get started

place a request through iLab >

DNA QC

DNA is assayed by qubit to determine concentration

Analytical Goals

Copy number analysis (CNA)

Sample Requirements

DNA Amount: 100ng
Minimum Input: 10ng
Volume: >10ul